Guselkumab
Uses of Guselkumab
Guselkumab treat adults with moderate to severe plaque psoriasis who may benefit from taking injections or pills (systemic therapy) or phototherapy (treatment using ultraviolet or UV light).
How Guselkumab Works
Guselkumab is a type of monoclonal antibody. It works by neutralizing the activity of a protein called IL-23, which is present at increased levels in people with psoriasis.
Side Effects of Guselkumab
Headache, Joint pain (arthralgia), Diarrhoea, Redness, irritation or pain at the injection site, Increased level of liver enzymes in the blood
Warnings
Kidney Limited Data
Guselkumab has not been studied in these patient populations. No dose recommendations can be made
Alcohol Limited Data
There is limited data if alcohol changes the effect of Guselkumab.
Pregnancy Limited Data
The use of Guselkumab in pregnant women has not been studied. The effect of Guselkumab on human pregnancy is unknown.
Driving Generally Safe
Guselkumab has no or negligible influence on the ability to drive and use machines.
Liver Limited Data
Guselkumab has not been studied in these patient populations. No dose recommendations can be made
Lactation Limited Data
It is unknown whether Guselkumab is excreted in human milk. You should discuss with your doctor whether to discontinue, or abstain from initiating treatment with Guselkumab.
Frequently Asked Questions
Written by Dr Sri Viknarajan, MD (Universiti Hasanuddin, Indonesia)
Reviewed by Dr Nur Syuhada binti Zulkifli, MD, Universiti Kebangsaan Malaysia (UKM).
