Iloprost
Uses of Iloprost
Iloprost is commonly used to treat Peripheral Vascular Disease, Pulmonary Hypertension, Raynaud's Disease
How Iloprost Works
Iloprost is a synthetic prostaglandin analogue which dilates the systemic and pulmonary blood vessel.
Side Effects of Iloprost
Facial flush, Headache, Nausea, Vomiting, Abdominal pain, Insomnia, Increase cough, Palpitation, Tongue pain, Dizziness
Warnings
Kidney Use With Care
There is no need for dosage adjustment in patients with renal impairment but the doses may need to be halved for dialysis patients.
Alcohol Safe
There is no clear contraindication on the consumption of alcohol when taking Iloprost.
Pregnancy Not Safe
There are no animal reproductive data available and limited human reproductive data suggests no fetal harm on using Iloprost. Iloprost should only be used with specialist advice in pregnant women.
Driving Not advisable
It is not advisable to drive when under Iloprost treatment due to its potential side effects such as headache and dizziness which can affect the ability to concentrate and drive.
Liver Use With Care
Dosage adjustment is needed in patients with moderate to severe hepatic impairment with close monitoring.
Lactation Not Advisable
It is not known whether Iloprost is excreted in human breast milk or not. Due to its potential toxicity towards the nursing infant, it is recommended either to stop breastfeeding or stop the treatment.
Frequently Asked Questions
Written by Dr Sri Viknarajan, MD (Universiti Hasanuddin, Indonesia)
Reviewed by Dr Nur Syuhada binti Zulkifli, MD, Universiti Kebangsaan Malaysia (UKM).
