Latanoprost
Uses of Latanoprost
Latanoprost is commonly used to treat Glaucoma, Ocular Hypertension
How Latanoprost Works
Latanoprost which has a similar structure to prostaglandin works by reducing the intra-ocular pressure by allowing more outflow of aqueous humour.
Side Effects of Latanoprost
Thickening and lengthening of the eyelashes, Eye irritation, Eyelid swelling, Blurred vision, Headache, Dizziness, Eye pain
Warnings
Kidney Safe If Prescribed
Although most of its metabolites is excreted via urine, there is no dosage adjustment needed in patients with renal impairment due to its negligible systemic exposure.
Alcohol Safe
There is no clear contraindication on the consumption of alcohol when taking Latanoprost.
Pregnancy Not Safe
Latanoprost has very limited data on human pregnancy and thus it is recommended to be used with the lowest effective dose during pregnancy to avoid systemic exposure towards the developing fetus.
Driving Not advisable
It is not advisable to drive when under Latanoprost treatment due to its potential side effects such as headache, dizziness other eye problems which can affect the ability to concentrate and drive.
Liver Limited Data
No dosage adjustment is needed in patients with hepatic impairment although it is being metabolised by the liver due to its negligible systemic exposure.
Lactation Limited Data
It is not known whether Latanoprost is excreted in human breast milk or not. It may be used with caution with the lowest effective dose.
Frequently Asked Questions
Written by Dr Sri Viknarajan, MD (Universiti Hasanuddin, Indonesia)
Reviewed by Dr Nur Syuhada binti Zulkifli, MD, Universiti Kebangsaan Malaysia (UKM).
