Levonorgestrel

Uses of Levonorgestrel

Levonorgestrel is commonly used for Contraception, Emergency Contraception, Menorrhagia, Hormone replacement therapy and Menopausal symptoms.

How Levonorgestrel Works

Levonorgestrel is a nortestosterone derivative which is an active metabolite of norgestrel. It acts as a potent inhibitor of ovulation and having androgenic activity allows contraceptive action and as emergency contraception alternatives.

Side Effects of Levonorgestrel

Nausea and vomiting, Headache, Dizziness, Breast discomfort, Weight changes, Changes of libido, Hair loss, Oedema

Warnings

Kidney Use With Care

Levonorgestrel should be used with caution in patients with severe kidney disease. Dose adjustment of Levonorgestrel may be needed. Please consult your doctor.

Alcohol Not Advisable

It is not advised to consume alcohol with Levonorgestrel. Taking Levonorgestrel with alcohol may worsen the CNS side effects such as headache, dizziness, lightheadedness, and nausea.

Pregnancy Not Safe - High Risk

Levonorgestrel is unsafe to use during pregnancy. Both animal and human studies have shown adverse effects on the fetus. The risk involved is clearly outweigh the potential benefits. Please consult your doctor.

Driving Generally Safe

Levonorgestrel usualy does not affect the ability to drive. Do not drive unless you are feeling well.

Liver Use With Care

Levonorgestrel is not recommended for patients with liver adenoma and any other hepatic impairment. Please consult your doctor.

Lactation Not Advisable

Levonorgestrel is not recommended to use during lactation because it is secreted into breast milk. However, the potential exposure of the nursing infant to Levonorgestrel can be reduced if the mother takes the tablet immediately after feeding and avoids nursing for at least the following 8 hours.

Frequently Asked Questions

Written by , MD (Universiti Hasanuddin, Indonesia)

Reviewed by Dr Nur Syuhada binti Zulkifli, MD, Universiti Kebangsaan Malaysia (UKM).