Linagliptin + Metformin

Uses of Linagliptin + Metformin

This medication belongs to the drug class of Antidiabetics and is indicated for the management of type 2 diabetes mellitus.

How Linagliptin + Metformin Works

Linagliptin works by inhibiting the enzyme dipeptidyl peptidase-4 (DPP-4), which increases the levels of incretin hormones, leading to increased insulin release and decreased glucagon levels. Metformin works by decreasing hepatic glucose production and increasing insulin sensitivity in peripheral tissues.

Side Effects of Linagliptin + Metformin

Common side effects may include diarrhea, nausea, and headache. Less common but serious side effects can include lactic acidosis, allergic reactions, and vitamin B12 deficiency.

Warnings

Kidney Safe If Prescribed

The medication is considered safe for use with proper medical guidance and monitoring, especially in individuals with kidney issues.

Alcohol Limited Data

Limited data are available regarding the interaction of this combination with alcohol. Caution is advised, and consultation with a healthcare professional is recommended before combining the two.

Pregnancy Limited Data

There is limited data on the safety of this combination during pregnancy. Consultation with a healthcare provider is recommended to assess potential risks and benefits.

Driving Generally Safe

This medication is generally considered safe for driving, but individual responses may vary. It is advisable to assess personal reaction before engaging in activities requiring alertness.

Liver Safe If Prescribed

The medication is considered safe for use with proper medical guidance and monitoring, especially in individuals with liver conditions.

Lactation Limited Data

Limited data are available regarding the safety of this combination during lactation. Consultation with a healthcare professional is advised to determine potential risks and benefits.

Written by , MD (Universiti Hasanuddin, Indonesia)

Reviewed by Dr Nur Syuhada binti Zulkifli, MD, Universiti Kebangsaan Malaysia (UKM).