Loratadine

Uses of Loratadine

Loratadine is commonly used in the treatment of allergic conditions, allergic eye disease, allergic skin conditions, nasal allergy symptoms, sneezing and runny nose due to allergies

How Loratadine Works

Loratadine is a piperidine derivative. It selectively inhibits the histamine H1- receptors on the effector cells in the periphery. It is a long-acting and non-sedating type of antihistamine.

Side Effects of Loratadine

Drowsiness, Nausea, Difficulty sleeping (insomnia), Dizziness, Fatigue, Dry mouth, Diarrhea, Palpitation, Abdominal Pain, Rash

Warnings

Kidney Use With Care

Loratadine should be used with caution in patients with kidney impairment and in elderly patients with reduced kidney function since it is eliminated through the kidneys. Dose adjustment of Loratadine is needed. Please consult your doctor before use.

Alcohol Not Advisable

It is unsafe to consume alcohol with Loratadine. Taking Loratadine with alcohol may also increase the risk of developing CNS depression

Pregnancy Safe If Prescribed

Loratadine should be safe as animals study showed no teratogenicity and fetal malformation recorded. Data of over 1000 women studied also showed no any negative effects on the fetal development.

Driving Generally Safe

Loratadine usually does not affect the ability to drive. Do not drive unless you are feeling well.

Liver Use With Care

Loratadine should be used with caution in patients with liver disorder. Dose adjustment of Loratadine may be needed. Please consult your doctor.

Lactation Not Advisable

Loratadine is probably unsafe to use during lactation. Loratadine is excreted into human breast milk hence should be avoided during lactation.

Frequently Asked Questions

Written by , MD (Universiti Hasanuddin, Indonesia)

Reviewed by Dr Nur Syuhada binti Zulkifli, MD, Universiti Kebangsaan Malaysia (UKM).