Metformin + Saxagliptin

Uses of Metformin + Saxagliptin

This combination medication belongs to the drug class of biguanides and dipeptidyl peptidase-4 (DPP-4) inhibitors. It is indicated for the management of type 2 diabetes mellitus.

How Metformin + Saxagliptin Works

Metformin works by decreasing glucose production in the liver and improving insulin sensitivity in the muscles. Saxagliptin works by increasing the levels of incretin hormones, which stimulate the release of insulin and reduce the levels of glucagon, leading to decreased blood glucose levels.

Side Effects of Metformin + Saxagliptin

Common side effects may include nausea, diarrhea, stomach upset, and headache. Less common but serious side effects may include pancreatitis, allergic reactions, and hypoglycemia.

Warnings

Kidney Safe If Prescribed

This medication is considered safe if prescribed for individuals with kidney issues. However, dosage adjustments may be necessary based on renal function.

Alcohol Limited Data

Limited data are available regarding the interaction of this combination with alcohol. Caution is advised, and consultation with a healthcare professional is recommended before combining the two.

Pregnancy Limited Data

There is limited data on the safety of this medication during pregnancy. Consultation with a healthcare provider is recommended.

Driving Generally Safe

This medication is generally safe to use while driving or operating machinery. However, individuals should monitor their blood glucose levels regularly to ensure they are not experiencing hypoglycemia, which can affect driving ability.

Liver Limited Data

Limited data are available on the effects of this medication on liver function. Caution is advised, especially for individuals with liver conditions. Consultation with a healthcare professional is recommended.

Lactation Limited Data

Limited data are available regarding the safety of this combination during lactation. Consultation with a healthcare professional is advised to determine potential risks and benefits.

Written by , MD (Universiti Hasanuddin, Indonesia)

Reviewed by Dr Nur Syuhada binti Zulkifli, MD, Universiti Kebangsaan Malaysia (UKM).

  • Products

    Available medicines with Metformin + Saxagliptin
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