Miconazole
Uses of Miconazole
Miconazole is commonly used to treat oral and vaginal candidiasis and fungal infections of skin and nails
How Miconazole Works
Miconazole is an antifungal agent which modifies the composition of fat components in the membrane and stopping the synthesis of an important compound called ergosterol. All of which causes the death of the fungal cells.
Side Effects of Miconazole
Topical: Contact dermatitis, Eyes and mucous membrane irritation Spray powder: Airway irritation General: Hypersensitivity reactions (including anaphylactic reactions), fatigue.
Warnings
Kidney Safe If Prescribed
It is safe for patients with kidney disease to use Miconazole. Dose adjustment is unnecessary.
Alcohol Safe
It is safe to consume alcohol with Miconazole.
Pregnancy Not Safe
Animal studies have shown no adverse effects on the foetus unless in large doses but this has not been confirmed in any well-controlled human studies. Therefore, please consult your doctor before using it.
Driving Generally Safe
Miconazole usually does not affect the ability to drive. Do not drive unless you are feeling well.
Liver Limited Data
Miconazole should be used with caution in patients with liver disease as liver is the main site of metabolism even though systemic absorption is minimal. Please consult your doctor before using it.
Lactation Limited Data
There are limited data on topical Miconazole being excreted in breast milk. Therefore, please consult your doctor before using it.
Frequently Asked Questions
Written by Dr Sri Viknarajan, MD (Universiti Hasanuddin, Indonesia)
Reviewed by Dr Nur Syuhada binti Zulkifli, MD, Universiti Kebangsaan Malaysia (UKM).
