Naloxone
Uses of Naloxone
How Naloxone Works
Naloxone competitively binds to opioid receptors in the brain, displacing opioids and reversing their effects. It quickly restores normal respiration and consciousness in individuals experiencing opioid overdose.
Side Effects of Naloxone
Common side effects may include withdrawal symptoms such as nausea, vomiting, sweating, and tremors.
Warnings
Kidney Limited Data
Limited data are available regarding the impact of Naloxone on kidney function. Consultation with a healthcare professional is recommended for individuals with kidney issues.
Alcohol Limited Data
Limited data are available regarding the interaction of Naloxone with alcohol. Caution is advised, and it is recommended to consult with a healthcare professional before combining the two.
Pregnancy Limited Data
There is limited data on the safety of Naloxone during pregnancy. Consultation with a healthcare provider is recommended to assess potential risks and benefits.
Driving Generally Safe
Naloxone typically does not impair the ability to drive. However, caution should be exercised as individual responses may vary, especially considering potential residual effects of opioids.
Liver Limited Data
Limited data are available on the effects of Naloxone on liver function. Caution is advised, especially for individuals with liver conditions. Consultation with a healthcare professional is recommended.
Lactation Limited Data
Limited data are available regarding the safety of Naloxone during lactation. Consultation with a healthcare professional is advised to determine potential risks and benefits.
Written by Dr Sri Viknarajan, MD (Universiti Hasanuddin, Indonesia)
Reviewed by Dr Nur Syuhada binti Zulkifli, MD, Universiti Kebangsaan Malaysia (UKM).
