Oestradiol Topical

Uses of Oestradiol Topical

Oestrogel is treatement used in postmenopausal women and also for those who have osteoporosis.

How Oestradiol Topical Works

The oestrogen in the body is replaced by Oestrogel. This is to ensure that you have the same amount of oestrogen as you did before menopause.

Side Effects of Oestradiol Topical

Painful Periods, Menstrual Periods Which Are Heavier Or Last Longer Than Usual, Abnormal Or Irregular Bleeding, White Or Yellow Vaginal Discharge Uncommon (May Affect Up To 1 In 1, Mood Swings, Migraine, Vertigo, Wind (Flatulence), Increase In The Volume Of The Uterus, Intolerance To Glucose, Which May Affect Your Blood Sugars, If You Have Epilepsy, Your Symptoms May Get Worse, High Blood Pressure, A Blood Test May Show Changes In The Way The Liver Is Working, Acne, Unusual Production Of Breast Milk, A Type Of Allergic Reaction Called Anaphylaxis (More Likely If You Have Had Allergic Reactions In The Past)

Warnings

Kidney Use With Care

In patients with renal dysfunction, they should be closely observed when using Oestradiol Topical as it may cause fluid retention.

Alcohol Not Advisable

It is not advisable to consume alcohol with oestradiol as research has found that the combination may increase the risk of breast cancer. Alcohol may increase the estrogen levels and thus, the extra estrogen and the synthetic oestradiol resulted in too much estrogen.

Pregnancy Not Safe - High Risk

Oestradiol Topical is contraindicated in pregnancy and thus the treatment should be withdrawn as soon as pregnancy is diagnosed.

Driving Generally Safe

Oestradiol Topical should not affect alertness or driving ability.

Liver Use With Care

It is recommended to avoid using Oestradiol Topical in patients with liver disease. If required, it should not be given during acute illness and need to be administered preferably through the transdermal route. This route bypasses the liver and thus, will not interfere with the hepatic enzymes and Oestradiol Topicals produced in the liver.

Lactation Not Advisable

Oestradiol Topical should not be used during breastfeeding.

Written by , MD (Universiti Hasanuddin, Indonesia)

Reviewed by Dr Nur Syuhada binti Zulkifli, MD, Universiti Kebangsaan Malaysia (UKM).