Permethrin
Uses of Permethrin
Permethrin is commonly used to treat Filariasis, Head Lice, Onchocerciasis Itchy Bumps On The Skin, Scabies, and Strongyloidiasis.
How Permethrin Works
It is a pyrethrin pediculocide and scabicide that treats parasite and fungal infection and also scabies. It interrupts Na ion influx through nerve cell membrane channels, delaying repolarisation and cause the parasites to paralyse and die.
Side Effects of Permethrin
Skin itchiness, Skin redness, Skin swelling, Burning or tingling sensation.
Warnings
Kidney Safe If Prescribed
There's no increased risk of toxic reactions in patients with renal impairment using Topical Permethrin as Permethrin is metabolized in liver and excreted in urine as inactive metabolite. Please consult your doctor.
Alcohol Safe
It is safe to consume alcohol with Permethrin because it is a topical drug. Ovicidal activity of Permethrin is increased by addition of an alcohol.However, if you feel any unfamiliar reactions when taking Permethrin with alcohol, please consult your doctor.
Pregnancy Maybe Safe
Permethrin may be safe to use during pregnancy. Animal studies do not show any adverse effects on the fetus, however, there are limited human studies. Please consult your doctor.
Driving Generally Safe
Permethrin usually does not affect the ability to drive. Do not drive unless you are feeling well.
Liver Limited Data
There is a hepatic metabolism of Permethrin, hence dose adjustment of Permethrin may be needed. Please consult your doctor.
Lactation Limited Data
it is not known whether Permethrin is excreted in human milk even though in cattle, low concentrations are excreted in the milk. Limited human data suggests that Permethrin does not represent a significant risk to the baby. Users should consider withholding treatment during nursing temporarily.
Frequently Asked Questions
Written by Dr Sri Viknarajan, MD (Universiti Hasanuddin, Indonesia)
Reviewed by Dr Nur Syuhada binti Zulkifli, MD, Universiti Kebangsaan Malaysia (UKM).
