Pertussis Toxoid
Uses of Pertussis Toxoid
Pertussis Toxoid is commonly used in the prevention of pertussis infection
How Pertussis Toxoid Works
Pertussis toxid is a component in the DPT vaccine that protects against Bordetella Pertussis infection by antibody production.
Side Effects of Pertussis Toxoid
Pain, Swelling & redness at injection site, Fever, Rash, Muscle weakness, Chills, Axillary lymph node swelling, Hypersensitivity
Warnings
Kidney Use With Care
It is recommended to administer the Pertussis Toxoid vaccine with caution in patients with renal impairment. There is limited data on the safety profile of the vaccine.
Alcohol Limited Data
Pertussis Toxoid vaccine is given during childhood and hence no data for the interaction with alcohol.
Pregnancy Not Safe
Animal studies have demonstrated that Pertussis Toxoid may cause adverse risks to the fetus and there are inadequate human studies. However, if there is a high risk of exposure to the pertussis infection in the community, the benefits of administering this vaccine over the potential risk should be assessed. The inactivated vaccine also may not cause any risk to the fetus.
Driving Generally Safe
Pertussis Toxoid usually does not affect the ability to drive. Do not drive unless you are feeling well.
Liver Limited Data
It is recommended to administer the Pertussis Toxoid vaccine with caution in patients with liver impairment. There is limited data on the safety profile of the vaccine.
Lactation Limited Data
It is not known whether Pertussis Toxoid is safe to be used during breastfeeding. The decision to administer the vaccine or continue breastfeeding depends on the benefits of vaccine to mother or benefits of breastfeeding to infant.
Written by Dr Sri Viknarajan, MD (Universiti Hasanuddin, Indonesia)
Reviewed by Dr Nur Syuhada binti Zulkifli, MD, Universiti Kebangsaan Malaysia (UKM).
