Potassium Clavulanate
Uses of Potassium Clavulanate
Potassium Clavulanate is commonly used in combination with Amoxycillin to treat Sinusitis, Interstitial Cystitis, Pyelonephritis, Cellulitis.
How Potassium Clavulanate Works
Potassium Clavulanate inhibits beta lactamase, an enzyme that allows bacteria to destroy amoxicillin making it resistant to the antibiotic.
Side Effects of Potassium Clavulanate
Fungal infections, Diarrhea, Nausea, Vomiting, Anaphylaxis, Headache, Dizziness, Antibiotic associated collitis, Skin rash, Pruritus
Warnings
Kidney Use With Care
Potassium Clavulanate should be used with caution in patients with severe kidney disease. Dose adjustment of Potassium Clavulanate may be needed. Please consult your doctor.
Alcohol Safe
It is safe to consume alcohol with Potassium Clavulanate as there is no known drug interaction.
Pregnancy Maybe Safe
Potassium Clavulanate may be unsafe to use during pregnancy. Animal studies do not show any adverse effect on the fetus, however, there are limited human studies. A single study indicated the risk of premature rupture of membrane and enterocolitis in neonates.
Driving Not advisable
Potassium Clavulanate may cause side effects such as dizziness and headache, all of which could affect your ability to concentrate and drive.
Liver Use With Care
In patients with liver disease, Potassium Clavulanate should be used with caution. Dose titration of Potassium Clavulanate may be needed.
Lactation Not Advisable
Potassium Clavulanate is excreted in human breast milk. There are risks of Diarrhea and fungal infections in the lactating infant.
Frequently Asked Questions
Written by Dr Sri Viknarajan, MD (Universiti Hasanuddin, Indonesia)
Reviewed by Dr Nur Syuhada binti Zulkifli, MD, Universiti Kebangsaan Malaysia (UKM).
