Primidone
Uses of Primidone
Primidone is commonly used to treat Epilepsy, Essential Tremor
How Primidone Works
Primidone works by decreasing the excitability of the neurons and thus increases the seizure threshold. This prevents seizures episodes to repeat.
Side Effects of Primidone
Drowsiness, Imbalance, Vertigo, Loss of appetite, Headache, Visual disturbance, Nausea, Vomiting, Dizziness, Fatigue
Warnings
Kidney Use With Care
Dosage adjustment may be needed in patients with renal impairment.
Alcohol Not Advisable
It is not advisable to consume alcohol when taking Primidone due to potential worsening of side effect on the central nervous system.
Pregnancy Limited Data
Primidone has been reported to cause serious birth defects as with other anticonvulsants. It is thus not recommended to be used during pregnancy.
Driving Not advisable
It is not advisable to drive after Primidone treatment due to its potential side effects such as dizziness and headache which can affect the ability to concentrate and drive.
Liver Safe If Prescribed
Dosage adjustment may be needed for patient with hepatic impairment with close monitoring as well.
Lactation Safe If Prescribed
Primidone is found in the human breastmilk in low quantity. The nursing infant should be monitored for an adverse reaction such as drowsiness and thus should be stopped from using if such adverse effect occurs.
Frequently Asked Questions
Written by Dr Sri Viknarajan, MD (Universiti Hasanuddin, Indonesia)
Reviewed by Dr Nur Syuhada binti Zulkifli, MD, Universiti Kebangsaan Malaysia (UKM).
