Ramipril
Uses of Ramipril
Ramipril is commonly used to treat Hypertension, Heart Attack, and Heart Failure
How Ramipril Works
Ramipril is an ACE inhibitor. It competitively inhibits ACE from converting angiotensin I to angiotensin II which cause an increase in plasma renin activity and reduction of aldosterone.
Side Effects of Ramipril
Cough, Syncope, Dyspnoea, Vomiting, Hypotension, Headache, Angioedema, Dizziness
Warnings
Kidney Use With Care
Dose adjustment of Ramipril is needed in a patient with kidney impairment.
Alcohol Not Advisable
It is not recommended to consume alcohol while taking this medication as it may potentiate Ramipril side effects of hypotension.
Pregnancy Not Safe
The ACE inhibitor has a small risk of teratogenicity if exposed during first trimester of pregnancy and exhibit possible effect of fetotoxicity during the second trimester onwards. Therefore Ramipril is contraindicated during pregnancy unless the benefits clearly outweigh the risks.
Driving Not advisable
Consumption of Ramipril may impair the ability to drive and operating machines. Only drive if you are feeling well.
Liver Limited Data
Dose adjustment is needed in a patient with liver failure and close monitoring should be done in these patients.
Lactation Limited Data
Limited data is available on the safety of Ramipril in breastfeeding. Therefore Ramipril is not recommended to be given to breastfeeding mothers.