Rivaroxaban
Uses of Rivaroxaban
Rivaroxaban is commonly used to treat Deep Vein Thrombosis, Heart Attack, Pulmonary Embolism, Stroke Prevention
How Rivaroxaban Works
Rivaroxaban is a selective Factor X inhibitor which is able to halt the clotting process irreversibly.
Side Effects of Rivaroxaban
Spontaneous bleeding, Anaemia, Abdominal pain, Back pain, Dizziness, Skin rash, Major bleeding event
Warnings
Kidney Use With Care
Dose adjustment is needed in patients with moderate to severe kidney impairment. Rivaroxaban is contraindicated in patients with creatinine clearance less than 15ml/min. Please consult your doctor.
Alcohol Not Advisable
Daily use of alcohol may cause stomach ulcer and spontaneous bleeding will occur when used with Rivaroxaban due to the impaired clotting process. Thus, it is not advisable to consume alcohol during the treatment with Rivaroxaban.
Pregnancy Not Safe
Animal studies have shown reproductive toxicity but there are limited data on the use of Rivaroxaban in pregnant women. Thus, Rivaroxaban is contraindicated during pregnancy due to potential reproductive toxicities.
Driving Generally Safe
Rivaroxaban usually does not affect the ability to drive. Do not drive unless you are feeling well.
Liver Use With Care
Rivaroxaban is contraindicated in patients with moderate to severe liver impairment. Please consult your doctor.
Lactation Not Advisable
Excretion of Rivaroxaban has been found in animal milk but it is unknown in human breast milk. Thus, Rivaroxaban is contraindicated during breastfeeding as the safety profile has not been established.
Frequently Asked Questions
Written by Dr Sri Viknarajan, MD (Universiti Hasanuddin, Indonesia)
Reviewed by Dr Nur Syuhada binti Zulkifli, MD, Universiti Kebangsaan Malaysia (UKM).
