Ropinirole
Uses of Ropinirole
Ropinirole is commonly used to treat Parkinson's Disease and Restless Leg Syndrome.
How Ropinirole Works
Ropinirole is a non-ergot dopamine agonist which has a higher affinity for D3 receptors which are located in the brain. It is able to increase the dopamine level and enhance the dopaminergic activity which in turn relieves the symptoms of Parkinson’s disease and restless leg syndrome.
Side Effects of Ropinirole
Sudden sleepiness, Drowsiness, Nausea, Abdominal pain, Dizziness, Headache, Hallucinations, Abnormal movements
Warnings
Kidney Use With Care
Dose adjustment is needed in patients with severe kidney impairment. It is contraindicated in patients with end-stage kidney disease under dialysis. Please consult your doctor.
Alcohol Not Advisable
Alcohol may accentuate the sedative effect caused by Ropinirole. Thus, it is not advisable to consume alcohol and Ropinirole concomitantly.
Pregnancy Not Safe
Animal studies have shown reproductive toxicities but there are limited data on the use of Ropinirole in pregnant women. Thus, it is not advisable to be used during pregnancy as risks cannot be excluded.
Driving Not advisable
Do not drive unless you are feeling well. Ropinirole may cause side effects such as impaired alertness, drowsiness or sleepiness, all of which could affect your ability to concentrate and drive.
Liver Use With Care
Caution use has to be practised in patients with moderate liver impairment. Ropinirole is contraindicated in patients with severe liver impairment.
Lactation Not Advisable
Ropinirole decreases the prolactin secretion in human, which will lead to the suppression of milk production. Thus, it should be discontinued during breastfeeding.