Sulphamethoxazole + Trimethoprim
Uses of Sulphamethoxazole + Trimethoprim
This medication, belonging to the class of antibacterials, is indicated for the treatment of various bacterial infections.
How Sulphamethoxazole + Trimethoprim Works
Sulphamethoxazole and trimethoprim work synergistically to inhibit the bacterial synthesis of tetrahydrofolic acid, essential for DNA synthesis, ultimately leading to bacterial cell death.
Side Effects of Sulphamethoxazole + Trimethoprim
Common side effects include nausea, vomiting, diarrhea, and allergic reactions. Serious adverse effects may include hematological disorders, Stevens-Johnson syndrome, and renal failure.
Warnings
Kidney Safe If Prescribed
Limited data are available regarding the impact of this medication on kidney function. Consultation with a healthcare professional is recommended, especially for individuals with kidney issues.
Alcohol Limited Data
Limited data are available regarding the interaction of this medication with alcohol. Caution is advised, and it is recommended to consult with a healthcare professional before combining the two.
Pregnancy Safe If Prescribed
This medication may be safe to use during pregnancy if prescribed by a healthcare professional after assessing potential risks and benefits.
Driving Use With Care
May cause dizziness or hypotension; assess individual response before driving or operating machinery.
Liver Limited Data
Limited data are available on the effects of this medication on liver function. Caution is advised, especially for individuals with liver conditions. Consultation with a healthcare professional is recommended.
Lactation Limited Data
Limited data are available regarding the safety of this medication during lactation. Consultation with a healthcare professional is advised.
Written by Dr Sri Viknarajan, MD (Universiti Hasanuddin, Indonesia)
Reviewed by Dr Nur Syuhada binti Zulkifli, MD, Universiti Kebangsaan Malaysia (UKM).
