Terazosin

Uses of Terazosin

Terazosin is commonly used to treat Benign Prostatic Hyperplasia, Heart Failure, Hypertension, and Raynaud's Disease.

How Terazosin Works

Terazosin is classified as an alpha-blocker. It competitively inhibits postsynaptic alpha receptors. As a result, it relaxes the peripheral blood vessels and reduces blood pressure. Besides, it also relieves the symptoms of benign prostate hyperplasia by reducing the smooth muscle tone of the bladder outlet.

Side Effects of Terazosin

Hypotension, Drowsiness, Palpitations, Visual disturbance, Weight gain, Body ache, Tinnitus, Urinary incontinence

Warnings

Kidney Safe If Prescribed

No dosage adjustments needed for patients with renal insufficiency.

Alcohol Not Advisable

It is unsafe to consume alcohol with Terazosin. Taking Terazosin with alcohol may have worsened the additive effects of Terazosin such as headache, dizziness, lightheadedness, feeling of increased heartbeats and low blood pressure.

Pregnancy Not Safe

Terazosin may be unsafe to use during pregnancy. Animal studies have shown side effects on the fetus, however, there are limited human studies and the safety profile during pregnancy is not established. It should not be used unless the potential benefit outweighs the risk. Please consult your doctor.

Driving Not advisable

Do not drive unless you are feeling well. Terazosin may cause side effects such as dizziness, headches or syncope, all of which could affect the ability to concentrate and drive.

Liver Limited Data

Terazosin is metabolized extensively by the liver, therefore, dose adjustment is needed in individuals wiith impaired liver function. For patients with severe hepatic impairment, Terazosin usage is not recommended.

Lactation Limited Data

Excretion of Terazosin in breast milk is still not known and the safety profile is not established in lactating women. Hence, it is not recommended during breastfeeding.

Frequently Asked Questions

Written by , MD (Universiti Hasanuddin, Indonesia)

Reviewed by Dr Nur Syuhada binti Zulkifli, MD, Universiti Kebangsaan Malaysia (UKM).