Tibolone
Uses of Tibolone
Tibolone is commonly used for Hormone Replacement Therapy and Post Menopausal Osteoporosis.
How Tibolone Works
Tibolone is a steroid that has estrogenic, progestogenic and androgenic effects which able to function as hormone replacement therapy for menopausal women to relieve their symptoms and prevent postmenopausal osteoporosis.
Side Effects of Tibolone
Weight gain, Dizziness, Rash, Headache, Visual disturbances, Gut disturbances, Facial hair growth, Liver dysfunction, Irregular vaginal bleeding
Warnings
Kidney Use With Care
Caution use has to be practised in patients with kidney impairment as fluid retention and body oedema may happen.
Alcohol Not Advisable
There is no known interaction between alcohol and Tibolone. However, there is an increased risk of breast cancer development in the long term when taking alcohol and Tibolone concomitantly. Thus, alcohol is not advisable when receiving Tibolone treatment.
Pregnancy Limited Data
There are no therapeutic indications of Tibolone during pregnancy so there are no clinical data to date. It is contraindicated during pregnancy and if women found pregnant during the treatment, Tibolone should be withdrawn immediately.
Driving Generally Safe
Tibolone usually does not affect the ability to drive. Do not drive unless you are feeling well.
Liver Use With Care
Tibolone should be discontinued in patients with abnormal liver function and should not be used in patients with severe liver impairment.
Lactation Not Advisable
Tibolone is contraindicated during breastfeeding.