Ticlopidine
Uses of Ticlopidine
Ticlopidine is commonly used to treat certain condition such as Blood Clots, and used in the treatment of Heart Attack, and Unstable Angina
How Ticlopidine Works
Ticlopidine which is an antiplatelet drug act by inhibiting platelets from clumping together best known as platelet aggregation. It is used as a treatment in a condition such as blood clots thus helping the blood flow smoothly in your body.
Side Effects of Ticlopidine
Diarrhea, Nausea, Dyspepsia, Bleeding tendency, Rashes on skin, Increase in serum cholesterol level, Increase of Liver Function Tests
Warnings
Kidney Use With Care
There is limited study, however, the use of this drug will decrease its plasma clearance and increase bleeding time in a patient with renal impairment. Please consult your doctor before taking this medication.
Alcohol Not Advisable
Taking alcohol while you are on Ticlopidine may increase the chance of bleeding in your gastrointestinal tract (GIT)
Pregnancy Maybe Safe
Since there are no controlled data in human pregnancy for Ticlopidine and animal studies couldn't demonstrate a risk to the fetus, therefore this medication is advised to be given only when it benefits the pregnant lady
Driving Not advisable
Do not drive unless you are feeling well. Ticlopidine may cause side effects such as dizziness, headches or nausea, all of which could affect the ability to concentrate and drive.
Liver Limited Data
There is a limited study done for the use of Ticlopidine in patients suffering from the hepatic disease. However, since Ticlopidine is metabolized in the liver, the adjustment of the dosage has to be made by the doctors before initiating the therapy. The use of Ticlopidine is not recommended in patients with severe hepatic disease.
Lactation Limited Data
It is not known whether Ticlopidine is excreted in the breast milk of humans, however, it is excreted in the rat's milk upon research. The decision to continue or stop breastfeeding has to be made by the doctor. Please consult your doctor for further information.
Written by Dr Sri Viknarajan, MD (Universiti Hasanuddin, Indonesia)
Reviewed by Dr Nur Syuhada binti Zulkifli, MD, Universiti Kebangsaan Malaysia (UKM).
