Tolterodine
Uses of Tolterodine
Tolterodine is commonly used to treat Overactive Bladder (OAB) Symptoms
How Tolterodine Works
Tolterodine is an antimuscarinic agent which competitively inhibits muscarinic receptors in the bladder and prevent bladder contraction, decrease detrusor muscle pressure. This mechanism helps in relieving symptoms of overactive bladder patients.
Side Effects of Tolterodine
Dry mouth, Dizziness, Sleepiness, Headache, Dry eyes, Visual disturbance, Abdominal pain, Altered bowel habit, Painful urination
Warnings
Kidney Use With Care
Dose adjustment may be needed in patients with kidney impairment. Please consult your doctor.
Alcohol Not Advisable
It is not advisable to consume alcohol and Tolterodine concomitantly as alcohol will accentuate the side effects of Tolterodine such as drowsiness and dizziness.
Pregnancy Not Safe
Animal studies have shown reproductive toxicities but there are limited data from the use of Tolterodine in pregnant women. Thus, Tolterodine is not advisable to be used during pregnancy. Please consult your doctor.
Driving Not advisable
Do not drive unless you are feeling well. Tolterodine may cause side effects such as visual disturbance or delaying reaction time, all of which could affect your ability to concentrate and drive.
Liver Limited Data
Dose adjustment may be needed in patients with mild to moderate liver impairment. It is not advisable to be used in patients with severe liver impairment. Please consult your doctor.
Lactation Limited Data
There are no data on the excretion of Tolterodine in human milk. Thus, Tolterodine is not advisable to be used during breastfeeding. Please consult your doctor.
Frequently Asked Questions
Written by Dr Sri Viknarajan, MD (Universiti Hasanuddin, Indonesia)
Reviewed by Dr Nur Syuhada binti Zulkifli, MD, Universiti Kebangsaan Malaysia (UKM).
