Tretinoin Topical

Uses of Tretinoin Topical

Topical tretinoin is a skin-only prescription medication (topical). It is used for acne therapy.

How Tretinoin Topical Works

Topical tretinoin active substance is tretinoin, which diminishes skin cell cohesion and leads to reduced formation of microcomedos. Skin cell renewal is also stimulated by Tretinoin.

Side Effects of Tretinoin Topical

Skin Irritation Such Burning, Stinging, Redness, Itching, Blistering, Crusting, Peeling, Swelling, Hyperpigmentation, Hypopigmentation, Increase In The Number Of Inflammatory Lesions Acne Flare And Increased Sensitivity Reaction To Sun Exposure Have Been Reported.

Warnings

Kidney Use With Care

Tretinoin Topical should use with caution in a patient with impaired kidney functions. A renal profile may be done before starting Tretinoin Topical therapy and the first month after initiating it.

Alcohol Not Advisable

Using alcohol with Tretinoin Topical may cause unfavourable interactions to occur whether it is used systemically or topically. Discuss with your healthcare professional the use of your medicine with alcohol.

Pregnancy Not Safe

Though there is a limited amount of data from the use of Tretinoin Topical in pregnant women but there is a high risk of severe malformation of the fetus, particularly if given during the first trimester, therefore, it must not be used during pregnancy, especially during the first trimester unless the condition of the mother requires treatment with Tretinoin Topical.

Driving Not advisable

Do not drive unless you are feeling well. Tretinoin Topical may cause side effects such as dizziness, headches, nausea or palpitations, all of which could affect the ability to concentrate and drive.

Liver Use With Care

Tell your doctor if you have any liver diseases since it is metabolized in the liver. Your doctor might have to adjust the dose accordingly. Monitoring is also needed as it can cause liver toxicity.

Lactation Not Advisable

It is excreted into the breast milk. Discontinue breastfeeding once Tretinoin Topical therapy is initiated

Frequently Asked Questions

Written by , MD (Universiti Hasanuddin, Indonesia)

Reviewed by Dr Nur Syuhada binti Zulkifli, MD, Universiti Kebangsaan Malaysia (UKM).