Trifluoperazine
Uses of Trifluoperazine
Trifluoperazine is commonly used to treat Nausea and Vomiting, Anxiety, Anxiety Disorder and Schizophrenia
How Trifluoperazine Works
Trifluoperazine is an antipsychotic which blocks the postsynaptic mesolimbic dopaminergic D1 and D2 receptors in the brain, which helps to control severely agitated or violent behaviour which can be seen in anxiety disorder or acute schizophrenia.
Side Effects of Trifluoperazine
Drowsiness, Dry mouth, Blurred vision, Sedation, Postural hypotension, Muscle weakness, Insomnia, Abnormal muscle movements
Warnings
Kidney Use With Care
Caution use of Trifluoperazine has to be practised in patients with kidney impairment.
Alcohol Not Advisable
It is not advisable to consume alcohol and Trifluoperazine concomitantly as alcohol will further depress the neurological function.
Pregnancy Not Safe
Animal studies have shown reproductive toxicities but the results are conflicting. There is no clinical evidence to show reproductive toxicities in pregnant women. Thus, Trifluoperazine is not advisable to be used during pregnancy unless necessary. Please consult your doctor.
Driving Not advisable
Do not drive unless you are feeling well. Trifluoperazine may cause side effects such as drowsiness, dizziness or visual disturbances, all of which could affect your ability to concentrate and drive.
Liver Limited Data
Caution use of Trifluoperazine has to be practised in patients with liver impairment.
Lactation Limited Data
Animal studies have shown secretion of Trifluoperazine in animal milk but there are limited data on human studies. Thus, Trifluoperazine is not advisable to be used during breastfeeding unless necessary. Please consult your doctor.
Frequently Asked Questions
Written by Dr Sri Viknarajan, MD (Universiti Hasanuddin, Indonesia)
Reviewed by Dr Nur Syuhada binti Zulkifli, MD, Universiti Kebangsaan Malaysia (UKM).
