Vardenafil
Uses of Vardenafil
Vardenafil is commonly used to treat Erectile Dysfunction.
How Vardenafil Works
Vardenafil is a phosphodiesterase inhibitor which able to bind strongly and inhibit the cGMP specific phosphodiesterase type 5 (PDE 5) in the corpus cavernosum around the penis. This can cause smooth muscle relaxation and increases the blood flow to the penis, maintain the erection in patients with erectile dysfunction.
Side Effects of Vardenafil
Headache, Dizziness, Flushing, Nasal congestion, Heartburn, Visual disturbances, Tinnitus
Warnings
Kidney Use With Care
Dose adjustment may be needed in patients with severe kidney impairment.
Alcohol Safe
There is no known interaction between alcohol and Vardenafil when used concomitantly.
Pregnancy Maybe Safe
Vardenafil is not used in women and no studies are conducted in pregnant women.
Driving Generally Safe
There are no studies of the Vardenafil on the ability to drive. Do not drive unless you are feeling well.
Liver Limited Data
Dose adjustment may be needed in patients with mild to moderate liver impairment whereas the use of Vardenafil is prohibited in patients with severe liver impairment.
Lactation Limited Data
Vardenafil is not used in women and no studies are conducted in breastfeeding women.
Frequently Asked Questions
Written by Dr Sri Viknarajan, MD (Universiti Hasanuddin, Indonesia)
Reviewed by Dr Nur Syuhada binti Zulkifli, MD, Universiti Kebangsaan Malaysia (UKM).
