Verapamil
Uses of Verapamil
Verapamil is commonly used to treat Angina Heart Related Chest Pain and Arrhythmias
How Verapamil Works
Verapamil is a calcium-channel blocker which acts by inhibiting the L-type calcium channels in the heart. It relaxes the heart and vascular smooth muscles and slows the automaticity of heart nodal conduction, subsequently reduces the heart rate and blood pressure.
Side Effects of Verapamil
Heart block, Bradycardia, Worsening of heart failure, Hypotension, Dizziness, Flushing, Peripheral oedema, Constipation, Liver dysfunction, Dyspnoea
Warnings
Kidney Use With Care
Caution use has to be exercised in patients with renal impairments as the disposition has not been fully established in this group of patients.
Alcohol Not Advisable
Verapamil is proved to increase the alcohol level in the blood and delay its elimination from the body. Thus, it is not advisable to take Verapamil and alcohol simultaneously as it can accentuate the effects of alcohol.
Pregnancy Not Safe
Although animal studies have shown no reproductive toxicity, Verapamil should not be used during pregnancy as it might cause relaxation of the uterus which may compromise the mother at term. Please consult your doctor.
Driving Not advisable
Do not drive unless you are feeling well. Verapamil may cause side effects such as drowsiness at the initial treatment which could affect your ability to concentrate and drive.
Liver Use With Care
Dose adjustment is needed in patients with liver impairment.
Lactation Not Advisable
Verapamil is known to be secreted in human milk. Thus, Verapamil is not advisable to be used during breastfeeding. Please consult your doctor.